2 edition of Factors influencing the administration of meperidine (pethidine) to postsurgical patients found in the catalog.
Factors influencing the administration of meperidine (pethidine) to postsurgical patients
Written in English
Ottawa General Hospital
|The Physical Object|
|Number of Pages||71|
After meperidine administration during labor, meperidine reaches its highest level in fetal tissues within hr. The highest levels of normeperidine, the active metabolite of meperidine, are, on the other hand, determined in fetal tissues by the time between administration of meperidine to the mother and delivery: the greater the drug-to. Meperidine has a risk for abuse and addiction, which can lead to overdose and death. Meperidine may also cause severe, possibly fatal, breathing problems. To lower your risk, your doctor should.
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is a platform for academics to share research papers. Meperidine is used to help relieve moderate to severe may also be used before and during surgery or other procedures. Meperidine belongs to a class of drugs known as opioid analgesics and is similar to works in the brain to change how your body feels and responds to pain.. Meperidine should not be used to treat long-term or ongoing pain.
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Data sources include IBM Watson Micromedex (updated 30 June ), Cerner Multum™ (updated 1 July ). Meperidine Hydrochloride Injection may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.
The patient should be cautioned accordingly. Meperidine Hydrochloride Injection, like other narcotics, may produce orthostatic hypotension in ambulatory. Meperidine is one of the most widely used analgesics in the United States, prescribed by up to 60% of physicians for acute painful conditions, and by over 20% for chronic pain (3).
PHARMACOKINETICS (Table 1) Absorption In contrast to morphine, absorption of meperidine after intramuscular administration is often variable, incomplete, and by: A better understanding of the process and common causes of meperidine use was sought through the development of a cause-and-effect (Ishikawa) diagram (Figure 4, p ) and a flow chart detailing the typical circumstances that surrounded its use (Figure 5, p ).The Ishikawa diagram helped highlight the multiple factors contributing to the drug’s overuse and was used to prioritize Cited by: Do not give meperidine by intravenous administration unless an opioid antagonist and the facilities for assisted or controlled respiration are immediately available.
Rapid intravenous injection of meperidine increases the incidence of adverse reactions; severe respiratory depression, apnea, hypotension, peripheral circulatory collapse, and. Assess BP, pulse, and respirations before and periodically during administration.
If respiratory rate is 10/min, assess level of sedation. Dose may need to be de. (NGOs), business lobbying Attempts to use information, research, or stakeholder opinion to influence governmental policy by an individual or organization., and other political activity.
As a result of the wide variety of influencing factors that tend to pull and push policy in different directions, public policy change often happens slowly.
The most common systemic medications are agonist (morphine, fentanyl, and meperidine) or agonist-antagonist (nalbuphine, butorphanol) opioids. Opioids influence nervous system of mother, yet a part of it crosses the placenta and affects the fetus.
It is noted that meperidine, applied subcutaneous; intramuscular; intravenous; and oral, is the. Administration of meperidine resulted in a significant decrease in both the overall incidence of shivering (87 to 35 per cent, p. The following points highlight the four main factors influencing learning.
The factors are: 1. Physiological Factors 2. Psychological Factors 3. Environmental Factors 4. Methodology of Instructions. Physiological Factors: The physiological factors are sense perception, physical health, fatigue time and day of learning, food and drink, age and atmospheric conditions. Sense-perception.
Drug Name Generic Name: meperidine hydrochloride (pethidine) Brand Name: Demerol Classification: Opioid agonist analgesic Pregnancy Category B Pregnancy Category D (prolonged use) Controlled Substance C-II Dosage & Route Available forms: Tablets—50, mg; syrup—50 mg/5 mL; injection—25, 50, 75, mg/mL ADULTS Relief of pain: Individualize dosage; 50– mg IM.
The administration of meperidine or other narcotics may obscure the diagnosis or clinical course in patients with acute abdominal conditions. Tolerance and Physical Dependence.
Tolerance is the need for increasing doses of opioids to maintain a defined effect such as analgesia (in the absence of disease progression or other external factors). Meperidine administration leads to significant decrease in blood pressure and cardiac output due to direct myocardial depressant effects and peripheral vasodilatation.
but additional factors. Meperidine appears to have a more rapid onset and shorter duration of action than does morphine. Following oral administration of meperidine, peak analgesia occurs within one hour and gradually declines over hours. Peak analgesia occurs about minutes after subcutaneous administration and minutes after IM administration.
Search the world's most comprehensive index of full-text books. My library. Meperidine Hydrochloride Injection, USP is an opioid agonist, available for intramuscular, subcutaneous or slow intravenous administration.
Each mL contains meperidine hydrochloride, either 25 mg, 50 mg or mg in Water for Injection. Buffered with acetic acid-sodium acetate. pH DOSAGE AND ADMINISTRATION • Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.
() • Individualize dosing based on the severity of pain, patient response, prior analgesic experience, and risk factors. The factors associated with fatal opioid-related overdose have been well characterized [2,7,12,14–21]. Patient-related factors include certain demographic characteristics and clinical comorbidities.
Men have a higher opioid-related overdose death rate, but the percentage rise in. There is a greater risk that you will overuse meperidine if you have or have ever had any of these conditions.
Talk to your health care provider immediately and ask for guidance if you think that you have an opioid addiction or call the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at HELP. Severe reactions may follow the administration of meperidine in patients being treated with MAO inhibitors.
Two basic types of interactions can be observed. The most prominent is an excitatory reaction (“serotonin syndrome”) with delirium, hyperthermia, headache, hyper- or hypotension, rigidity, convulsions, coma, and death. Public Policy and Factors Influencing Public Policy Dr.
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